Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpxATwo-component sensor kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 sensor protein CpxA or EcfB or Ssd or Eup or b3911 or c4863 or z5456 or ecs4837 SWALL:CPXA_ECOLI (SWALL:P08336) (457 aa) fasta scores: E(): 1.8e-151, 80.04% id in 456 aa. (456 aa)    
Predicted Functional Partners:
cpxR
Two-component response regulator; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein CpxR or b3912 or z5457 or ecs4838 or sf3991 SWALL:CPXR_ECOLI (SWALL:P16244) (232 aa) fasta scores: E(): 5.3e-78, 88.79% id in 232 aa.
 
 0.999
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 0.988
cutF
Similar to Escherichia coli copper homeostasis protein CutF precursor or NlpE or b0192 SWALL:CUTF_ECOLI (SWALL:P40710) (236 aa) fasta scores: E(): 8.9e-40, 49.55% id in 224 aa, and to Yersinia pestis putative copper homeostasis lipoprotein CutF or ypo1067 or y3110 SWALL:AAM86660 (EMBL:AJ414146) (242 aa) fasta scores: E(): 1.5e-46, 53.71% id in 229 aa.
     
 0.959
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
0.927
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
  
 0.922
ECA0889
Two-component system response regulator; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein CpxR or b3912 or z5457 or ecs4838 or sf3991 SWALL:CPXR_ECOLI (SWALL:P16244) (232 aa) fasta scores: E(): 3.5e-31, 44.93% id in 227 aa, and to Yersinia pestis putative two-component system response regulator ypo2998 or cpxr or y1482 SWALL:Q8ZCI9 (EMBL:AJ414154) (227 aa) fasta scores: E(): 1.3e-67, 77.97% id in 227 aa.
 
 0.917
ompR
Two-component osmolarity response regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri transcriptional regulatory protein OmpR or OmpB or Kmt or b3405 or c4181 or z4760 or ecs4247 or stm3502 or sty4294 or t4004 or sf3424 SWALL:OMPR_ECOLI (SWALL:P03025) (239 aa) fasta scores: E(): 3.6e-91, 99.16% id in 239 aa.
 
 0.910
pehR
Two-component response regulator of virulence determinants; Similar to Pectobacterium carotovorum subsp. carotovorum response regulator PehR SWALL:Q9ZIN9 (EMBL:AF022772) (227 aa) fasta scores: E(): 1.5e-76, 91.26% id in 229 aa, and to Erwinia chrysanthemi PhoP protein phoP SWALL:CAD33237 (EMBL:AJ489252) (222 aa) fasta scores: E(): 7.2e-74, 87.83% id in 222 aa.
 
 0.903
baeR
Two-component system response regulator; Similar to Escherichia coli, and Escherichia coli O6 transcriptional regulatory protein BaeR baer or b2079 or c2605 SWALL:BAER_ECOLI (SWALL:P30846) (240 aa) fasta scores: E(): 5.7e-63, 73.12% id in 227 aa.
 
 0.889
qseB
Two-component system response regulator; Similar to Escherichia coli transcriptional regulatory protein QseB SWALL:QSEB_ECOLI (SWALL:P52076) (219 aa) fasta scores: E(): 3.1e-59, 68.34% id in 218 aa.
 
 0.860
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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