Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ECA4325DeoR-family trancriptional regulator; Similar to Yersinia pestis orf40 ypo1938 or y2373 SWALL:Q9ZC48 (EMBL:AL031866) (256 aa) fasta scores: E(): 1.7e-68, 72.22% id in 252 aa, and to Escherichia coli hypothetical transcriptional regulator ygbi or b2735 SWALL:YGBI_ECOLI (SWALL:P52598) (265 aa) fasta scores: E(): 4.4e-58, 62.3% id in 252 aa. (253 aa)    
Predicted Functional Partners:
ECA4326
Putative membrane protein; No significant database matches.
       0.773
fruK
1-phosphofructokinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 1-phosphofructokinase FruK or Fpk or b2168 or c2703 or z3426 or ecs3060 or sf2253 SWALL:K1PF_ECOLI (SWALL:P23539) (312 aa) fasta scores: E(): 7.8e-108, 90.7% id in 312 aa; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.693
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
 
  
 0.691
otnK
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate.
 
   
 0.664
otnC
Putative sugar aldolase; Catalyzes the decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate (DHAP) and CO(2). Belongs to the aldolase class II family. AraD/FucA subfamily.
 
   
 0.646
otnI
Putative isomerase; Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo- tetronate.
 
   
 0.643
ltnD
Putative oxidoreductase; Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
     
 0.535
ECA4323
Putative exported protein; Similar to Yersinia pestis hypothetical protein ypo1620 or y1780 SWALL:Q8ZFR8 (EMBL:AJ414149) (137 aa) fasta scores: E(): 5.7e-33, 60.58% id in 137 aa.
       0.508
ECA4324
Similar to Yersinia pestis hypothetical protein ypo1619 or y1779 SWALL:AAM85347 (EMBL:AJ414149) (189 aa) fasta scores: E(): 8.4e-51, 70.21% id in 188 aa, and to Escherichia coli O6 hypothetical protein c0078 SWALL:AAN78574 (EMBL:AE016755) (78 aa) fasta scores: E(): 0.00011, 43.42% id in 76 aa.
       0.508
gntP-2
Gluconate permease; Similar to Corynebacterium glutamicum gluconate permease GntP or cgl2908 SWALL:Q9AL75 (EMBL:AJ296014) (463 aa) fasta scores: E(): 3.8e-52, 39.47% id in 461 aa, and to Escherichia coli putative transport protein b2740 SWALL:Q9F8R6 (EMBL:AF242209) (454 aa) fasta scores: E(): 7.1e-115, 73.78% id in 454 aa.
 
     0.422
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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