STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
otnIPutative isomerase; Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo- tetronate. (262 aa)    
Predicted Functional Partners:
otnK
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate.
 
  
 0.944
ltnD
Putative oxidoreductase; Catalyzes oxidation of L-threonate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
 
 0.932
otnC
Putative sugar aldolase; Catalyzes the decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate (DHAP) and CO(2). Belongs to the aldolase class II family. AraD/FucA subfamily.
 
  
 0.896
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
 
 0.790
ECA0489
Similar to Escherichia coli 2-hydroxy-3-oxopropionate reductase GlxR or GlxB1 or b0509 SWALL:GLXR_ECOLI (SWALL:P77161) (292 aa) fasta scores: E(): 4.9e-13, 26.16% id in 279 aa, and to Pseudomonas aeruginosa probable 3-hydroxyisobutyrate dehydrogenase pa3312 SWALL:Q9HYT2 (EMBL:AE004753) (296 aa) fasta scores: E(): 3.4e-17, 31.09% id in 283 aa.
 
 
 0.741
ECA4325
DeoR-family trancriptional regulator; Similar to Yersinia pestis orf40 ypo1938 or y2373 SWALL:Q9ZC48 (EMBL:AL031866) (256 aa) fasta scores: E(): 1.7e-68, 72.22% id in 252 aa, and to Escherichia coli hypothetical transcriptional regulator ygbi or b2735 SWALL:YGBI_ECOLI (SWALL:P52598) (265 aa) fasta scores: E(): 4.4e-58, 62.3% id in 252 aa.
 
   
 0.643
tkrA
2-ketogluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
  
 
  0.615
ECA3947
Similar to Pseudomonas putida D-isomer specific 2-hydroxyacid dehydrogenase family protein pp4589 SWALL:AAN70162 (EMBL:AE016791) (310 aa) fasta scores: E(): 4.3e-61, 56.63% id in 309 aa, and to Pseudomonas aeruginosa probable 2-hydroxyacid dehydrogenase pa1296 SWALL:Q9I448 (EMBL:AE004559) (310 aa) fasta scores: E(): 5.3e-54, 51.94% id in 308 aa.
  
 
  0.601
hprA
Glycerate dehydrogenase; Similar to Methylobacterium extorquens glycerate dehydrogenase HprA SWALL:DHGY_METEX (SWALL:Q59516) (313 aa) fasta scores: E(): 9.9e-43, 42.03% id in 314 aa, and to Haemophilus influenzae putative 2-hydroxyacid dehydrogenase Hi1556 hi1556 SWALL:YF56_HAEIN (SWALL:P45250) (315 aa) fasta scores: E(): 6.7e-68, 55.06% id in 316 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.559
ECA4326
Putative membrane protein; No significant database matches.
       0.503
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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