STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsECell division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division. (223 aa)    
Predicted Functional Partners:
ftsX
Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 0.996
ftsY
Cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
     
 0.861
ECA0170
Putative exported peptidase; Similar to Yersinia pestis putative membrane protein y0078 SWALL:AAM83673 (EMBL:AE013608) (456 aa) fasta scores: E(): 2.5e-78, 71.87% id in 416 aa, and to Salmonella typhi hypothetical protein Sty4090 SWALL:Q8Z2F1 (EMBL:AL627280) (427 aa) fasta scores: E(): 9.5e-72, 67.49% id in 403 aa, and to Escherichia coli hypothetical protein YibP SWALL:YIBP_ECOLI (SWALL:P37690) (419 aa) fasta scores: E(): 3.5e-71, 66.5% id in 403 aa.
 
   
 0.616
dppD
Dipeptide transport ATP-binding protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri dipeptide transport ATP-binding protein DppD or b3541 or z4958 or ecs4421 or sf3576 SWALL:DPPD_ECOLI (SWALL:P37314) (327 aa) fasta scores: E(): 1.9e-103, 88.07% id in 327 aa; Belongs to the ABC transporter superfamily.
 
    
0.567
oppD
Similar to Salmonella typhimurium oligopeptide transport ATP-binding protein OppD or stm1743 SWALL:OPPD_SALTY (SWALL:P04285) (335 aa) fasta scores: E(): 3.4e-102, 86.29% id in 321 aa; Belongs to the ABC transporter superfamily.
 
    
0.559
ECA2960
Similar to Rhizobium loti probable peptide ABC transporter ATP-binding abc transporter protein msi192 SWALL:Q8KJF3 (EMBL:AL672113) (335 aa) fasta scores: E(): 1.6e-55, 52.81% id in 320 aa, and to Bacillus halodurans oligopeptide ABC transporter appd or bh0350 SWALL:Q9KFX0 (EMBL:AP001508) (329 aa) fasta scores: E(): 6.5e-57, 53.53% id in 325 aa.
 
    
0.555
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
  
 0.547
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.545
rpsK
30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
     0.532
tsaC
Putative DNA topoisomerase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
 
     0.517
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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