STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ftsECell division ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division. (223 aa)    
Predicted Functional Partners:
ftsX
Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 0.999
ECA0170
Putative exported peptidase; Similar to Yersinia pestis putative membrane protein y0078 SWALL:AAM83673 (EMBL:AE013608) (456 aa) fasta scores: E(): 2.5e-78, 71.87% id in 416 aa, and to Salmonella typhi hypothetical protein Sty4090 SWALL:Q8Z2F1 (EMBL:AL627280) (427 aa) fasta scores: E(): 9.5e-72, 67.49% id in 403 aa, and to Escherichia coli hypothetical protein YibP SWALL:YIBP_ECOLI (SWALL:P37690) (419 aa) fasta scores: E(): 3.5e-71, 66.5% id in 403 aa.
 
 
 
 0.950
zipA
Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
 
 
 0.903
ftsY
Cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
     
 0.848
bspA
Putative mechanosensitive ion channel; Similar to Erwinia chrysanthemi BspA protein precursor BspA SWALL:Q9EV03 (EMBL:AJ251781) (1106 aa) fasta scores: E(): 0, 77.97% id in 1108 aa, and to Yersinia pestis putative membrane transport protein ypo0363 or y0619 SWALL:AAM84207 (EMBL:AJ414142) (1119 aa) fasta scores: E(): 0, 71.54% id in 1114 aa.
   
 
 0.720
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 
 0.657
polA
Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.602
ftsW
Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
   
 0.600
ftsI
Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
   
 0.596
mraZ
Conserved hypothetical protein; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
  
   
 0.585
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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