STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zntAHeavy metal-transporting ATPase; Similar to Escherichia coli lead, cadmium, zinc and mercury transporting ATPase ZntA or b3469 SWALL:ATZN_ECOLI (SWALL:P37617) (732 aa) fasta scores: E(): 1.4e-152, 62.53% id in 710 aa, and to Proteus mirabilis putative P-type cation-translocating membrane ATPase PpaA SWALL:O33448 (EMBL:AJ001437) (692 aa) fasta scores: E(): 5.2e-155, 65.26% id in 688 aa. (787 aa)    
Predicted Functional Partners:
copA
Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa.
 
 
0.900
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
  
 0.696
cueR
Copper efflux regulator; Similar to Escherichia coli, and Shigella flexneri transcriptional regulator CueR or b0487 or sf0432 SWALL:CUER_ECOLI (SWALL:P77565) (135 aa) fasta scores: E(): 8.4e-34, 72.51% id in 131 aa.
  
  
 0.645
cepA
Cation efflux pump; Cation-efflux transporter that may have a role in detoxification.
 
 
 0.629
zitB
Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
  
  
 0.563
pitA
Low-affinity inorganic phosphate transporter; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 low-affinity inorganic phosphate transporter 1 PitA or Pit or b3493 or c4291 or z4893 or ecs4365 SWALL:PITA_ECOLI (SWALL:P37308) (499 aa) fasta scores: E(): 1.3e-136, 70.37% id in 503 aa.
   
  
 0.542
ECA4351
Similar to Yersinia pestis putative membrane protein ypo3819 or y0411 SWALL:Q8ZAI2 (EMBL:AJ414159) (208 aa) fasta scores: E(): 7e-55, 66.98% id in 209 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein yhhn or stm3575 or sty4236 SWALL:Q8XH18 (EMBL:AE008864) (208 aa) fasta scores: E(): 5.2e-51, 63.63% id in 209 aa.
       0.532
ribD
Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.510
amtB
Probable ammonium transporter; Similar to Escherichia coli, and Escherichia coli O157:H7 probable ammonium transporter AmtB or b0451 or z0563 or ecs0505 SWALL:AMTB_ECOLI (SWALL:P37905) (428 aa) fasta scores: E(): 4.1e-125, 76.11% id in 427 aa.
   
  
 0.502
gor
Similar to Escherichia coli glutathione reductase Gor SWALL:GSHR_ECOLI (SWALL:P06715) (450 aa) fasta scores: E(): 3.8e-155, 86.66% id in 450 aa and to to Yersinia pestis glutathione reductase Gor SWALL:Q8ZA43 (EMBL:AJ414160) (450 aa) fasta scores: E(): 7.8e-158, 88.66% id in 450 aa.
     
 0.490
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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