STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ECA4354Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (225 aa)    
Predicted Functional Partners:
putA
Bifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
     
  0.902
queF
Putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
  
  
 0.865
grxA
Glutaredoxin 1; Similar to Escherichia coli, and Shigella flexneri glutaredoxin 1 GrxA or Grx or b0849 or sf0802 SWALL:GLR1_ECOLI (SWALL:P00277) (85 aa) fasta scores: E(): 6e-21, 69.88% id in 83 aa.
  
    0.698
ECA1754
Similar to Yersinia pestis putative membrane protein ypo1438 or y2732 SWALL:AAM86284 (EMBL:AJ414148) (712 aa) fasta scores: E(): 0, 75.03% id in 709 aa, and to Shigella flexneri orf, conserved hypothetical protein yccs or sf0962 SWALL:AAN42590 (EMBL:AE015125) (721 aa) fasta scores: E(): 5.4e-206, 71% id in 707 aa.
  
     0.518
sirA
SirA protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
  
    0.493
dcrB
Putative lipoprotein; Similar to Escherichia coli, and Shigella flexneri dcrb protein precursor DcrB or b3472 or sf3490 SWALL:DCRB_ECOLI (SWALL:P37620) (185 aa) fasta scores: E(): 2.8e-37, 61.9% id in 189 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane lipoprotein stm3580 or sty4231 SWALL:Q8XFQ6 (EMBL:AE008865) (185 aa) fasta scores: E(): 7.2e-38, 63.83% id in 188 aa.
       0.474
rnb
Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
  
     0.445
tehB
Similar to Escherichia coli tellurite resistance protein TehB or b1430 SWALL:TEHB_ECOLI (SWALL:P25397) (197 aa) fasta scores: E(): 3.4e-41, 60.73% id in 191 aa, and to Yersinia pestis tehb protein TehB or ypo1949 or y2361 SWALL:Q9ZC59 (EMBL:AL031866) (295 aa) fasta scores: E(): 3.3e-81, 70.21% id in 282 aa.
  
     0.431
ECA2661
Similar to Yersinia pestis putative membrane protein ypo1361 or y2818 SWALL:Q8ZGE0 (EMBL:AJ414147) (298 aa) fasta scores: E(): 4.1e-83, 74.16% id in 298 aa, and to Salmonella typhimurium putative inner membrane protein ybje or stm0938 SWALL:Q8ZQE7 (EMBL:AE008740) (299 aa) fasta scores: E(): 4.3e-75, 67.33% id in 300 aa.
  
    0.428
ECA0018
Conserved hypothetical protein; Similar to Pectobacterium carotovorum subsp. carotovorum YihD SWALL:Q9RB12 (EMBL:AF146615) (89 aa) fasta scores: E(): 6.6e-33, 98.87% id in 89 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protein YihD SWALL:YIHD_ECOLI (SWALL:P32126) (89 aa) fasta scores: E(): 1.8e-26, 80.89% id in 89 aa.
  
     0.413
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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