STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4381Putative DNA-binding protein; Similar to Shigella flexneri yjjm gene product yjjm or sf4388 SWALL:AAN45804 (EMBL:AE015445) (304 aa) fasta scores: E(): 2.8e-109, 88.81% id in 304 aa, and to Escherichia coli hypothetical protein yjjm or b4357 SWALL:YJJM_ECOLI (SWALL:P39399) (268 aa) fasta scores: E(): 6.2e-95, 88.06% id in 268 aa. (304 aa)    
Predicted Functional Partners:
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
 
  
 0.957
ECA4382
Putative zinc-binding dehydrogenase; Similar to Escherichia coli hypothetical zinc-type alcohol dehydrogenase-like protein yjjn or b4358 SWALL:YJJN_ECOLI (SWALL:P39400) (337 aa) fasta scores: E(): 2.4e-105, 85.16% id in 337 aa, and to Salmonella typhimurium putative zinc-binding dehydrogenase stm3082 SWALL:Q8ZM59 (EMBL:AE008841) (338 aa) fasta scores: E(): 6.5e-63, 53.84% id in 338 aa.
 
   
 0.799
ECA1947
Putative sugar-binding periplasmic protein (pseudogene); 1 probable transmembrane helix predicted for ECA1945 by TMHMM2.0 at aa 34-56.
  
     0.715
cobB
Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily.
  
    0.582
ECA3925
Similar to Salmonella typhi hypothetical protein Sty3249 SWALL:Q8Z3V2 (EMBL:AL627277) (187 aa) fasta scores: E(): 8.8e-53, 71.65% id in 187 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri protein yqge or b2948 or c3534 or sf2939 SWALL:YQGE_ECOLI (SWALL:P52049) (187 aa) fasta scores: E(): 1.6e-52, 69.51% id in 187 aa; Belongs to the UPF0301 (AlgH) family.
  
    0.575
uxaB2
Altronate oxidoreductase; Similar to Escherichia coli, and Escherichia coli O157:H7 altronate oxidoreductase UxaB or b1521 or z2184 or ecs2128 SWALL:UXAB_ECOLI (SWALL:P24214) (483 aa) fasta scores: E(): 2.9e-146, 72.67% id in 483 aa. Also similar to ECA0646 (69.278% id. in 485 aa overlap).
     
 0.544
ECA4380
Probable sugar transporter; Similar to Escherichia coli hypothetical transport protein yjjl or b4356 SWALL:YJJL_ECOLI (SWALL:P39398) (453 aa) fasta scores: E(): 4.2e-172, 91.17% id in 453 aa, and to Bacillus subtilis hexuronate transporter ExuT SWALL:EXUT_BACSU (SWALL:O34456) (422 aa) fasta scores: E(): 1e-42, 30.56% id in 409 aa.
 
  
 0.543
xylR
Xylose operon regulatory protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 xylose operon regulatory protein XylR SWALL:XYLR_ECOLI (SWALL:P37390) (392 aa) fasta scores: E(): 2.5e-127, 81.02% id in 390 aa.
  
  
 0.490
ECA3160
Similar to Salmonella typhimurium putative transcriptional regulator stm2195 SWALL:Q8ZNL4 (EMBL:AE008798) (129 aa) fasta scores: E(): 3.8e-14, 38.68% id in 137 aa, and to Salmonella typhi putative DNA-binding protein sty2429 SWALL:Q8Z5A0 (EMBL:AL627273) (129 aa) fasta scores: E(): 4.4e-14, 38.68% id in 137 aa.
  
  
 0.459
ECA1054
Similar to Escherichia coli putative prophage cp4-6 integrase IntF or b0281 SWALL:INTF_ECOLI (SWALL:P71298) (466 aa) fasta scores: E(): 0.0029, 24.6% id in 443 aa, and to Xylella fastidiosa phage-related integrase xf0631 SWALL:Q9PFM6 (EMBL:AE003908) (413 aa) fasta scores: E(): 1.2, 24.71% id in 445 aa.
  
     0.441
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.