STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4401Putative membrane protein; Similar to Yersinia pestis hypothetical membrane protein ypo4083 or y4100 SWALL:Y4I3_YERPE (SWALL:Q8Z9V7) (552 aa) fasta scores: E(): 2.4e-166, 80.07% id in 552 aa, and to Salmonella typhimurium hypothetical membrane protein yide or stm3807 SWALL:YIDE_SALTY (SWALL:Q8ZL04) (553 aa) fasta scores: E(): 5.2e-158, 76.5% id in 549 aa. (552 aa)    
Predicted Functional Partners:
ibpB
Heat shock protein B; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
       0.450
ECA3865
Similar to Yersinia pestis putative membrane protein ypo0485 SWALL:Q8ZIL1 (EMBL:AJ414143) (151 aa) fasta scores: E(): 1.8e-48, 85.06% id in 154 aa, and to Salmonella typhi putative membrane protein sty4898 SWALL:Q8Z0W0 (EMBL:AL627284) (157 aa) fasta scores: E(): 2.1e-43, 71.97% id in 157 aa.
 
     0.441
glpB
Anaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.
  
     0.431
ECA2743
Similar to Escherichia coli hypothetical protein yech or b1906 SWALL:YECH_ECOLI (SWALL:P46887) (79 aa) fasta scores: E(): 5.8e-18, 62.02% id in 79 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yech or stm1936 or sty2144 SWALL:Q8XGI3 (EMBL:AE008786) (79 aa) fasta scores: E(): 1.1e-16, 59.49% id in 79 aa.
  
     0.424
frdD
Fumarate reductase 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
  
     0.413
dcuB
Anaerobic C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
  
     0.403
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.