STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dgoA2Similar to the N-terminal region of Escherichia coli DgoA protein [includes: 2-dehydro-3-deoxyphosphogalactonate aldolase; galactonate dehydratase] DgoA or DgoD or b3692 SWALL:DGOA_ECOLI (SWALL:P31458) (587 aa) fasta scores: E(): 1.3e-38, 61.08% id in 203 aa, and similar, over the entire length, to Xanthomonas axonopodis 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase DgoA or xac1766 SWALL:Q8PLM9 (EMBL:AE011808) (210 aa) fasta scores: E(): 2.8e-38, 56.63% id in 196 aa. (205 aa)    
Predicted Functional Partners:
dgoK
Similar to Escherichia coli 2-dehydro-3-deoxygalactonokinase DgoK or b3693 SWALL:DGOK_ECOLI (SWALL:P31459) (292 aa) fasta scores: E(): 3.5e-61, 54.76% id in 294 aa.
 
 
 0.998
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
 0.948
eda
Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri Khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase and 2- dehydro-3-deoxyphosphogluconate aldolase Eda or Hga or KdgA or b1850 or c2263 or z2902 or ecs2560 or sf1860 SWALL:ALKH_ECOLI (SWALL:P10177) (213 aa) fasta scores: E(): 1.2e-67, 89.15% id in 212 aa, and to Erwinia chrysanthemi khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase Eda or KdgA SWALL:ALKH_ERWCH (SWALL:P38448) (213 aa) fasta scores: E(): 7e-67, 89.2% id in 213 aa.
  
  
 
0.928
dgoA1
DgoA protein [includes: 2-dehydro-3-deoxyphosphogalactonate aldolase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate.
 
   
 0.895
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
 
 0.815
dgoR
Similar to Escherichia coli galactonate operon transcriptional repressor DgoR or b3694/b3695 SWALL:DGOR_ECOLI (SWALL:P31460) (229 aa) fasta scores: E(): 6.9e-70, 80.61% id in 227 aa; putative GntR-family transcriptional regulator.
     
 0.796
kdgK
2-dehydro-3-deoxygluconokinase; Similar to Erwinia chrysanthemi 2-dehydro-3-deoxygluconokinase KdgK SWALL:KDGK_ERWCH (SWALL:P45416) (310 aa) fasta scores: E(): 1.4e-100, 82.25% id in 310 aa.
 
 
 0.782
glk
Glucokinase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucokinase Glk or b2388 or z3654 or ecs3268 SWALL:GLK_ECOLI (SWALL:P46880) (321 aa) fasta scores: E(): 7.3e-98, 76.32% id in 321 aa; Belongs to the bacterial glucokinase family.
 
 
 0.678
napF
Ferredoxin-type protein; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.
     
  0.641
ECA0661
Similar to Erwinia chrysanthemi PTS system, beta-glucoside-specific IIabc component ArbF SWALL:PTBA_ERWCH (SWALL:P26207) (631 aa) fasta scores: E(): 2.4e-60, 42.76% id in 622 aa, and to Escherichia coli PTS system, beta-glucoside-specific IIabc component BglF or BglC or BglS or b3722 SWALL:PTBA_ECOLI (SWALL:P08722) (625 aa) fasta scores: E(): 6.6e-60, 42.09% id in 639 aa.
    
 0.631
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (52%) [HD]