STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4424Similar to Rhizobium meliloti putative nucleoside hydrolase protein r00415 or smc01105 SWALL:Q92SI0 (EMBL:AL591783) (314 aa) fasta scores: E(): 6.6e-47, 46.32% id in 313 aa, and to Agrobacterium tumefaciens inosine-uridine preferring nucleoside hydrolase iunh or atu0374 or agr_c_654 SWALL:Q8UIC3 (EMBL:AE009008) (333 aa) fasta scores: E(): 4.3e-50, 49.83% id in 309 aa; Belongs to the IUNH family. (317 aa)    
Predicted Functional Partners:
ECA4423
Similar to Rhizobium meliloti putative nucleoside hydrolase protein r00415 or smc01105 SWALL:Q92SI0 (EMBL:AL591783) (314 aa) fasta scores: E(): 1.3e-49, 47.74% id in 310 aa, and to Agrobacterium tumefaciens inosine-uridine preferring nucleoside hydrolase IunH or atu0374 or agr_c_654 SWALL:Q8UIC3 (EMBL:AE009008) (333 aa) fasta scores: E(): 2.5e-48, 44.37% id in 311 aa; Belongs to the IUNH family.
 
  
 
0.978
ECA0053
Putative phosphodiesterase; Similar to Vibrio cholerae 2`,3`-cyclic-nucleotide 2`-phosphodiesterase, putative vc2416 SWALL:Q9KPF2 (EMBL:AE004311) (634 aa) fasta scores: E(): 9.2e-161, 66.4% id in 634 aa; Belongs to the 5'-nucleotidase family.
  
 
  0.911
cpdB
Similar to Escherichia coli 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor CpdB or b4213 SWALL:CN16_ECOLI (SWALL:P08331) (647 aa) fasta scores: E(): 9.6e-198, 76.68% id in 639 aa; Belongs to the 5'-nucleotidase family.
  
 
  0.911
hpt
Similar to Salmonella typhimurium hypoxanthine phosphoribosyltransferase Hpt or stm0170 SWALL:HPRT_SALTY (SWALL:O33799) (178 aa) fasta scores: E(): 1.2e-54, 86.2% id in 174 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypoxanthine phosphoribosyltransferase Hpt or b0125 or c0154 or sf0122 SWALL:HPRT_ECOLI (SWALL:P36766) (178 aa) fasta scores: E(): 2.4e-54, 84.48% id in 174 aa; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.909
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.908
add
Similar to Escherichia coli adenosine deaminase Add or b1623 SWALL:ADD_ECOLI (SWALL:P22333) (333 aa) fasta scores: E(): 2.2e-89, 71.77% id in 333 aa; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
 
 0.908
gpt
Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
 0.908
ushA
Similar to Escherichia coli protein UshA precursor [includes: UDP-sugar hydrolase and 5'-nucleotidase] UshA or b0480 SWALL:USHA_ECOLI (SWALL:P07024) (550 aa) fasta scores: E(): 1.6e-157, 71.5% id in 551 aa; Belongs to the 5'-nucleotidase family.
  
 
  0.904
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
     
 0.904
cobB
Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily.
   
 
 0.903
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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