STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4464Putative permease; Similar to Yersinia pestis putative membrane/transport protein, symporter y4121 SWALL:AAM87663 (EMBL:AE014013) (461 aa) fasta scores: E(): 3e-144, 89.13% id in 460 aa, and to Salmonella typhimurium putative xanthine/uracil permeases family yieg or stm3851 SWALL:Q8ZKX8 (EMBL:AE008879) (487 aa) fasta scores: E(): 2e-135, 83.59% id in 451 aa. (470 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.842
ECA4465
Putative membrane protein; Similar to Salmonella typhimurium, and Salmonella typhi phage shock protein PspD or stm1687 or sty1374 SWALL:Q8XEN8 (EMBL:AE008775) (72 aa) fasta scores: E(): 2.4, 31.08% id in 74 aa, and to Salmonella typhi phage shock protein D PspD or t1592 SWALL:AAO69223 (EMBL:AE016839) (72 aa) fasta scores: E(): 2.4, 31.08% id in 74 aa.
       0.773
uraA
Uracil permease; Similar to Escherichia coli, and Escherichia coli O157:H7 uracil permease UraA or b2497 or z3760 or ecs3359 SWALL:URAA_ECOLI (SWALL:P33780) (429 aa) fasta scores: E(): 2.7e-132, 86.85% id in 426 aa.
 
  
 0.623
ECA4466
Similar to Yersinia pestis putative haloacid dehalogenase-like hydrolase ypo4108 or y4122 SWALL:Q8Z9T7 (EMBL:AJ414160) (222 aa) fasta scores: E(): 1.9e-58, 64.54% id in 220 aa, and to Escherichia coli hypothetical protein yieh or b3715 SWALL:YIEH_ECOLI (SWALL:P31467) (221 aa) fasta scores: E(): 1.1e-50, 57.46% id in 221 aa.
  
    0.611
ECA0035
Putative purine permease; Similar to Yersinia pestis putative membrane permease ypo0034 SWALL:Q8ZJQ8 (EMBL:AJ414141) (461 aa) fasta scores: E(): 1.8e-149, 86.98% id in 461 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 putative purine permease YicE SWALL:YICE_ECOLI (SWALL:P27432) (463 aa) fasta scores: E(): 3.4e-148, 85.65% id in 460 aa.
 
  
 0.589
YjcD
Putative permease; Similar to Yersinia pestis putative xanthine/uracil permease ypo3629 or y0239 SWALL:Q8ZB00 (EMBL:AJ414158) (451 aa) fasta scores: E(): 7.4e-142, 87.58% id in 451 aa, and to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein yjcd yjcd or b4064 or z5663 or ecs5046 SWALL:YJCD_ECOLI (SWALL:P32702) (449 aa) fasta scores: E(): 4.7e-133, 82.58% id in 448 aa.
  
   
0.532
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
     
 0.482
purD
Similar to Escherichia coli phosphoribosylamine--glycine ligase PurD or b4005 SWALL:PUR2_ECOLI (SWALL:P15640) (429 aa) fasta scores: E(): 1.2e-130, 79.67% id in 428 aa; Belongs to the GARS family.
  
  
 0.475
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.472
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri phosphoribosylaminoimidazole-succinocarboxamide synthase PurC or b2476 or c3004 or z3735 or ecs3338 or sf2519 SWALL:PUR7_ECOLI (SWALL:P21155) (237 aa) fasta scores: E(): 1.1e-84, 90.71% id in 237 aa; Belongs to the SAICAR synthetase family.
  
  
 0.462
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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