STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4492Similar to Actinobacillus actinomycetemcomitans 3-oxoacyl-[acyl-carrier protein] reductase fabG SWALL:FABG_ACTAC (SWALL:P70720) (242 aa) fasta scores: E(): 1.5e-46, 56.19% id in 242 aa, and to Escherichia coli O6 3-oxoacyl-[acyl-carrier protein] reductase c1187 SWALL:Q8FJ14 (EMBL:AE016758) (243 aa) fasta scores: E(): 7.9e-68, 79.83% id in 243 aa. (243 aa)    
Predicted Functional Partners:
ECA4491
Putative beta-ketoacyl-ACP synthase; Similar to Actinobacillus actinomycetemcomitans beta-ketoacyl-ACP synthase IV FabF SWALL:P70719 (EMBL:D88189) (414 aa) fasta scores: E(): 5.7e-93, 56.52% id in 414 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 3-oxoacyl-[acyl-carrier-protein] synthase II fabf or fabj or b1095 or c1365 or z1734 or ecs1473 or sf1099 SWALL:AAN42718 (EMBL:Z34979) (413 aa) fasta scores: E(): 8.9e-46, 38.74% id in 413 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.997
ECA4494
Putative beta-ketoacyl synthase; Similar to Escherichia coli O157:H7 putative 3-oxoacyl-[ACP] synthase z4863 or ecs4338 SWALL:Q8X6K9 (EMBL:AE005571) (389 aa) fasta scores: E(): 2e-98, 69.58% id in 388 aa, and to Vibrio vulnificus 3-oxoacyl-(acyl-carrier-protein) synthase vv10058 SWALL:AAO08600 (EMBL:AE016797) (395 aa) fasta scores: E(): 1.3e-65, 49.48% id in 390 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.996
fabD
Similar to Escherichia coli, and Escherichia coli O6 malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 or c1361 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 1.7e-91, 78.82% id in 307 aa.
 0.969
fabB
Similar to Escherichia coli, and Escherichia coli O6 3-oxoacyl-[acyl-carrier-protein] synthase I FabB or FabC or b2323 or c2869 SWALL:FABB_ECOLI (SWALL:P14926) (406 aa) fasta scores: E(): 1.3e-137, 92.32% id in 404 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.963
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.962
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH]; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM or b1288 or z2512 or ecs1861 or sf1293 SWALL:FABI_ECOLI (SWALL:P29132) (261 aa) fasta scores: E(): 1.6e-84, 86.97% id in 261 aa.
  
 
 0.954
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.949
fabA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
 
 0.948
ECA4503
Similar to Escherichia coli O157:H7 putative acyl carrier protein z4854 or ecs4329 SWALL:Q8X6N3 (EMBL:AE005571) (83 aa) fasta scores: E(): 1.1e-18, 70.73% id in 82 aa, and to Vibrio vulnificus acyl carrier protein vv10048 SWALL:AAO08590 (EMBL:AE016797) (84 aa) fasta scores: E(): 1.9e-14, 56.79% id in 81 aa.
 
  0.931
ECA4493
Putative beta-hydroxydecanoyl-ACP dehydrase; Similar to Streptococcus pyogenes, and Streptococcus pyogenes FabZ or spy1746 or spym18_1818 SWALL:FABZ_STRPY (SWALL:P58175) (139 aa) fasta scores: E(): 8e-05, 32.84% id in 137 aa, and to Escherichia coli O157:H7 putative beta-hydroxydecanoyl-ACP dehydrase z4864 or ecs4339 SWALL:Q8X6K7 (EMBL:AE005571) (154 aa) fasta scores: E(): 2.8e-29, 51.59% id in 157 aa.
 
  
  0.925
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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