STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4492Similar to Actinobacillus actinomycetemcomitans 3-oxoacyl-[acyl-carrier protein] reductase fabG SWALL:FABG_ACTAC (SWALL:P70720) (242 aa) fasta scores: E(): 1.5e-46, 56.19% id in 242 aa, and to Escherichia coli O6 3-oxoacyl-[acyl-carrier protein] reductase c1187 SWALL:Q8FJ14 (EMBL:AE016758) (243 aa) fasta scores: E(): 7.9e-68, 79.83% id in 243 aa. (243 aa)    
Predicted Functional Partners:
ECA4494
Putative beta-ketoacyl synthase; Similar to Escherichia coli O157:H7 putative 3-oxoacyl-[ACP] synthase z4863 or ecs4338 SWALL:Q8X6K9 (EMBL:AE005571) (389 aa) fasta scores: E(): 2e-98, 69.58% id in 388 aa, and to Vibrio vulnificus 3-oxoacyl-(acyl-carrier-protein) synthase vv10058 SWALL:AAO08600 (EMBL:AE016797) (395 aa) fasta scores: E(): 1.3e-65, 49.48% id in 390 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.993
ECA4491
Putative beta-ketoacyl-ACP synthase; Similar to Actinobacillus actinomycetemcomitans beta-ketoacyl-ACP synthase IV FabF SWALL:P70719 (EMBL:D88189) (414 aa) fasta scores: E(): 5.7e-93, 56.52% id in 414 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 3-oxoacyl-[acyl-carrier-protein] synthase II fabf or fabj or b1095 or c1365 or z1734 or ecs1473 or sf1099 SWALL:AAN42718 (EMBL:Z34979) (413 aa) fasta scores: E(): 8.9e-46, 38.74% id in 413 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.985
fabB
Similar to Escherichia coli, and Escherichia coli O6 3-oxoacyl-[acyl-carrier-protein] synthase I FabB or FabC or b2323 or c2869 SWALL:FABB_ECOLI (SWALL:P14926) (406 aa) fasta scores: E(): 1.3e-137, 92.32% id in 404 aa; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.943
fabZ
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 0.928
ECA4500
Similar to Escherichia coli O6 conserved hypothetical protein c1196 SWALL:AAN79658 (EMBL:AE016758) (125 aa) fasta scores: E(): 3.4e-24, 54.78% id in 115 aa, and to Vibrio vulnificus 3-hydroxymyristoyl/3-hydroxydecanoyl- vv10051 SWALL:AAO08593 (EMBL:AE016797) (123 aa) fasta scores: E(): 2.4e-14, 49.12% id in 114 aa.
 
 
 0.927
fabA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
 0.925
ECA4498
Putative thioesterase; Similar to Escherichia coli O6 hypothetical protein c1193 SWALL:AAN79655 (EMBL:AE016758) (140 aa) fasta scores: E(): 5.7e-45, 76.42% id in 140 aa, and to Vibrio vulnificus predicted thioesterase vv10054 SWALL:AAO08596 (EMBL:AE016797) (148 aa) fasta scores: E(): 4.2e-27, 52.3% id in 130 aa.
 
 
 
 0.925
ECA0109
Similar to Escherichia coli O6 hypothetical protein c1689 SWALL:AAN80156 (EMBL:AE016760) (347 aa) fasta scores: E(): 6e-85, 68.73% id in 323 aa, and to Yersinia pestis hypothetical y2334 SWALL:AAM85893 (EMBL:AE013835) (179 aa) fasta scores: E(): 2.2e-47, 73.83% id in 172 aa.
 
 
 0.923
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.923
ECA4499
Putative glycosyl transferase; Similar to Escherichia coli O6 putative enzyme c1194 SWALL:AAN79656 (EMBL:AE016758) (540 aa) fasta scores: E(): 2.2e-148, 66.17% id in 541 aa, and to Vibrio vulnificus predicted acyltransferase vv10052 SWALL:AAO08594 (EMBL:AE016797) (569 aa) fasta scores: E(): 1.5e-122, 54% id in 574 aa.
 
 
 
 0.923
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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