STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (264 aa)    
Predicted Functional Partners:
thiD
Similar to Escherichia coli phosphomethylpyrimidine kinase ThiD or b2103 SWALL:THID_ECOLI (SWALL:P76422) (266 aa) fasta scores: E(): 1.1e-78, 78.27% id in 267 aa.
  
 0.998
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.993
thiG
Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.685
thiC
Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.665
thiH
Similar to Escherichia coli thiazole biosynthesis protein ThiH or b3990 SWALL:THIH_ECOLI (SWALL:P30140) (376 aa) fasta scores: E(): 2.6e-125, 81.03% id in 369 aa.
  
  
 0.540
thiS
Thiamine biosynthesis protein; Similar to Escherichia coli this protein ThiS or ThiG1 or b3991.1 SWALL:THIS_ECOLI (SWALL:O32583) (66 aa) fasta scores: E(): 2.4e-12, 56.06% id in 66 aa.
  
    0.518
thiF
Thiamine biosynthesis adenylyltransferase; Similar to Escherichia coli adenylyltransferase ThiF or b3992 SWALL:THIF_ECOLI (SWALL:P30138) (251 aa) fasta scores: E(): 7e-59, 60.56% id in 246 aa.
  
  
 0.483
psiE
Putative membrane protein; Similar to Yersinia pestis PsiE protein homolog PsiE or ypo3717 or y0025 SWALL:Q8ZAS3 (EMBL:AJ414158) (135 aa) fasta scores: E(): 2.3e-39, 75.55% id in 135 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri PsiE protein PsiE or b4030 or c5001 or sf4175 SWALL:AAN45596 (EMBL:J02812) (136 aa) fasta scores: E(): 1.9e-35, 71.53% id in 130 aa.
       0.453
ECA0932
Permease; Similar to Escherichia coli, and Escherichia coli O6 cytosine permease CodB or b0336 or c0455 SWALL:CODB_ECOLI (SWALL:P25525) (419 aa) fasta scores: E(): 5.8e-25, 28.73% id in 428 aa, and to Streptomyces coelicolor putative cytosine permease sco0572 or sc5g5.04C SWALL:Q93RZ8 (EMBL:AL939106) (466 aa) fasta scores: E(): 2.4e-55, 40.19% id in 413 aa.
  
    0.430
ECA2641
Permease; Similar to Escherichia coli, and Escherichia coli O6 cytosine permease CodB or b0336 or c0455 SWALL:CODB_ECOLI (SWALL:P25525) (419 aa) fasta scores: E(): 2.4e-20, 28% id in 350 aa, and to Bacillus halodurans cytosine permease bh1882 SWALL:Q9KBP3 (EMBL:AP001513) (445 aa) fasta scores: E(): 1.4e-50, 36.59% id in 429 aa.
  
    0.430
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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