Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aceEPyruvate dehydrogenase E1 component. (887 aa)    
Predicted Functional Partners:
aceF
Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
lpdA
Dihydrolipoamide dehydrogenase.
 
 0.997
porB
Putative pyruvate-flavodoxin oxidoreductase.
     
 0.975
maeB
NADP-dependent malate dehydrogenase (decarboxylating).
  
 
 0.948
pykF
Pyruvate kinase.
  
 
 0.922
pykA
Pyruvate kinase A; Belongs to the pyruvate kinase family.
  
 
 0.922
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.918
sfcA
NAD-linked malic enzyme; malate oxidoreductase.
    
 0.912
ldhA
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.910
poxB
Pyruvate dehydrogenase.
     
 0.908
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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