STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htrAProtease DO precursor; heat shock protein HtrA; Belongs to the peptidase S1C family. (475 aa)    
Predicted Functional Partners:
surA
Survival protein SurA precursor.
     
 0.927
fkpA
FKBP-type peptidyl-prolyl isomerase.
   
 
 0.917
ompH
Outer membrane protein OmpH precursor; Belongs to the skp family.
  
   
 0.889
ompC
Outer membrane protein C; Belongs to the Gram-negative porin family.
  
 
 
 0.854
ompA
Outer membrane protein A; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 
 0.851
aroD
3-dehydroquinate dehydratase; Belongs to the type-I 3-dehydroquinase family.
      
 0.832
rseA
sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...]
  
 
 0.786
dnaK
DnaK protein (heat shock protein 70).
  
 
 0.715
yaeT
Outer membrane protein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
  
   
 0.714
cpxA
Two-component sensor kinase protein.
 
  
 0.684
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.