| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SBG_2235 | apt | SBG_2235 | SBG_0429 | Putative amidotransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.926 |
| SBG_2235 | gmk | SBG_2235 | SBG_3321 | Putative amidotransferase. | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.915 |
| SBG_2235 | gpt | SBG_2235 | SBG_0258 | Putative amidotransferase. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.926 |
| SBG_2235 | gsk | SBG_2235 | SBG_0437 | Putative amidotransferase. | Inosine-guanosine kinase. | 0.900 |
| SBG_2235 | guaA | SBG_2235 | SBG_2288 | Putative amidotransferase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.913 |
| SBG_2235 | guaB | SBG_2235 | SBG_2289 | Putative amidotransferase. | Inosine-5'-monophosphate dehydrogenase. | 0.982 |
| SBG_2235 | guaC | SBG_2235 | SBG_0132 | Putative amidotransferase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.957 |
| SBG_2235 | hpt | SBG_2235 | SBG_0162 | Putative amidotransferase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.918 |
| SBG_2235 | rdgB | SBG_2235 | SBG_2703 | Putative amidotransferase. | Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.907 |
| apt | SBG_2235 | SBG_0429 | SBG_2235 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative amidotransferase. | 0.926 |
| apt | gmk | SBG_0429 | SBG_3321 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.948 |
| apt | gpt | SBG_0429 | SBG_0258 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.946 |
| apt | gsk | SBG_0429 | SBG_0437 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-guanosine kinase. | 0.922 |
| apt | guaA | SBG_0429 | SBG_2288 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.987 |
| apt | guaB | SBG_0429 | SBG_2289 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase. | 0.499 |
| apt | guaC | SBG_0429 | SBG_0132 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.924 |
| apt | hpt | SBG_0429 | SBG_0162 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.934 |
| apt | pup | SBG_0429 | SBG_3981 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase. | 0.914 |
| gmk | SBG_2235 | SBG_3321 | SBG_2235 | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative amidotransferase. | 0.915 |
| gmk | apt | SBG_3321 | SBG_0429 | 5'guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.948 |