| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| accC | guaA | SBG_2997 | SBG_2288 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.549 |
| accC | ribD | SBG_2997 | SBG_0369 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Riboflavin biosynthesis protein RibD. | 0.910 |
| guaA | accC | SBG_2288 | SBG_2997 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.549 |
| guaA | ribA | SBG_2288 | SBG_1574 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.525 |
| guaA | ribD | SBG_2288 | SBG_0369 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibD. | 0.912 |
| guaA | ribF | SBG_2288 | SBG_0043 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.429 |
| nrdR | ribD | SBG_0368 | SBG_0369 | Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Riboflavin biosynthesis protein RibD. | 0.946 |
| nrdR | ribH | SBG_0368 | SBG_0370 | Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 6,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase beta chain). | 0.641 |
| ribA | guaA | SBG_1574 | SBG_2288 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.525 |
| ribA | ribB | SBG_1574 | SBG_2788 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 3,4-dihydroxy-2-butanone 4-phosphate synthase. | 0.984 |
| ribA | ribD | SBG_1574 | SBG_0369 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | Riboflavin biosynthesis protein RibD. | 0.999 |
| ribA | ribE | SBG_1574 | SBG_1249 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | Riboflavin synthase alpha chain. | 0.995 |
| ribA | ribH | SBG_1574 | SBG_0370 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 6,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase beta chain). | 0.982 |
| ribB | ribA | SBG_2788 | SBG_1574 | 3,4-dihydroxy-2-butanone 4-phosphate synthase. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.984 |
| ribB | ribD | SBG_2788 | SBG_0369 | 3,4-dihydroxy-2-butanone 4-phosphate synthase. | Riboflavin biosynthesis protein RibD. | 0.997 |
| ribB | ribE | SBG_2788 | SBG_1249 | 3,4-dihydroxy-2-butanone 4-phosphate synthase. | Riboflavin synthase alpha chain. | 0.997 |
| ribB | ribF | SBG_2788 | SBG_0043 | 3,4-dihydroxy-2-butanone 4-phosphate synthase. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.428 |
| ribB | ribH | SBG_2788 | SBG_0370 | 3,4-dihydroxy-2-butanone 4-phosphate synthase. | 6,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase beta chain). | 0.997 |
| ribD | accC | SBG_0369 | SBG_2997 | Riboflavin biosynthesis protein RibD. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.910 |
| ribD | guaA | SBG_0369 | SBG_2288 | Riboflavin biosynthesis protein RibD. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.912 |