STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SBG_1095Conserved hypothetical protein (pseudogene); Signal peptide predicted for SBG1094 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.992 between residues 40 and 41. (156 aa)    
Predicted Functional Partners:
SBOV14671_1
Conserved hypothetical protein.
  
   
 0.856
hslS
Heat shock protein B; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
 
  
0.761
clpA
ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.
  
 
 0.622
clpV1_3
Type VI secretion protein (ClpV); Belongs to the ClpA/ClpB family.
  
 
 0.622
clpB
ClpB protein (heat shock protein f84.1); Belongs to the ClpA/ClpB family.
  
 
 0.622
htpG
Heat shock protein HtpG.
  
 
 0.515
hslO_1
Heat shock protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.
  
  
 0.501
dnaK
DnaK protein (heat shock protein 70).
  
 
 0.450
grpE
Heat shock protein GrpE (heat shock protein b25.3) (hsp24); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the rea [...]
  
  
 0.437
dnaJ
DnaJ protein.
  
 
 0.426
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.