STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhEHypothetical integral membrane protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily. (457 aa)    
Predicted Functional Partners:
mdfA
Multidrug translocase MdfA.
     
 0.896
emrB
Multidrug resistance protein B; Belongs to the major facilitator superfamily.
      
 0.831
acrA
Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.827
mepA
Penicillin-insensitive murein endopeptidase precursor; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family.
      
 0.827
ybjZ
Conserved hypothetical ABC transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
     
 0.789
acrD
Putative efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   
 0.784
tolC
Outer membrane protein TolC precursor.
   
  
 0.771
yegN
Putative RND-family transporter protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
      
 0.623
emrA
Multidrug resistance protein A.
      
 0.552
ribE
Riboflavin synthase alpha chain.
  
    0.545
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.