| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SBOV18761_3 | prc | SBG_1703 | SBG_1699 | Conserved hypothetical protein; The similarities to mce (mammalian cell entry) proteins originally described in Mycobacterium tuberculosis. | Tail-specific protease precursor; Belongs to the peptidase S41A family. | 0.405 |
| SBOV18761_3 | proQ | SBG_1703 | SBG_1700 | Conserved hypothetical protein; The similarities to mce (mammalian cell entry) proteins originally described in Mycobacterium tuberculosis. | ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.431 |
| SBOV18761_3 | yebR_1 | SBG_1703 | SBG_1701 | Conserved hypothetical protein; The similarities to mce (mammalian cell entry) proteins originally described in Mycobacterium tuberculosis. | Conserved hypothetical protein. | 0.601 |
| SBOV18761_3 | yebS_1 | SBG_1703 | SBG_1702 | Conserved hypothetical protein; The similarities to mce (mammalian cell entry) proteins originally described in Mycobacterium tuberculosis. | Putative membrane protein. | 0.977 |
| SBOV18761_3 | yebU | SBG_1703 | SBG_1704 | Conserved hypothetical protein; The similarities to mce (mammalian cell entry) proteins originally described in Mycobacterium tuberculosis. | rRNA (cytosine-C(5)-)-methyltransferase; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.813 |
| metE | metH | SBG_3499 | SBG_3657 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.993 |
| metE | metK | SBG_3499 | SBG_2690 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.980 |
| metE | mmuM | SBG_3499 | SBG_0327 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Homocysteine s-methyltransferase. | 0.926 |
| metE | tyrB | SBG_3499 | SBG_3693 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Aromatic-amino-acid aminotransferase. | 0.906 |
| metE | yebR_1 | SBG_3499 | SBG_1701 | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Conserved hypothetical protein. | 0.900 |
| metH | metE | SBG_3657 | SBG_3499 | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.993 |
| metH | metK | SBG_3657 | SBG_2690 | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.961 |
| metH | mmuM | SBG_3657 | SBG_0327 | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homocysteine s-methyltransferase. | 0.949 |
| metH | tyrB | SBG_3657 | SBG_3693 | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aromatic-amino-acid aminotransferase. | 0.912 |
| metH | yebR_1 | SBG_3657 | SBG_1701 | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Conserved hypothetical protein. | 0.900 |
| metK | metE | SBG_2690 | SBG_3499 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.980 |
| metK | metH | SBG_2690 | SBG_3657 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.961 |
| metK | mmuM | SBG_2690 | SBG_0327 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Homocysteine s-methyltransferase. | 0.925 |
| metK | tyrB | SBG_2690 | SBG_3693 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Aromatic-amino-acid aminotransferase. | 0.906 |
| metK | yebR_1 | SBG_2690 | SBG_1701 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Conserved hypothetical protein. | 0.900 |