STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menDMenaquinone biosynthesis protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (556 aa)    
Predicted Functional Partners:
yfbB
Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
 
 0.999
menF
Isochorismate synthase.
 
 0.998
menB
Naphthoate synthase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
  
 0.991
entC
Isochorismate synthase EntC.
 
 0.983
menE
O-succinylbenzoic acid-CoA ligase.
 
   
 0.962
menC
O-succinylbenzoate-CoA synthase; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
   
 0.951
menA
Menaquinone biosynthetic protein.
 
   
 0.839
ydiI
Conserved hypothetical protein.
 
   
 0.575
ybdB
Conserved hypothetical protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family.
 
   
 0.550
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
      
 0.531
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.