| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amiA | hemF | SBG_2246 | SBG_2247 | Putative N-acetylmuramoyl-L-alanine amidase. | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.877 |
| hemB | hemE | SBG_0328 | SBG_3641 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.840 |
| hemB | hemF | SBG_0328 | SBG_2247 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.612 |
| hemB | hemG | SBG_0328 | SBG_3518 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Protoporphyrinogen oxidase. | 0.468 |
| hemB | hemH | SBG_0328 | SBG_0435 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.717 |
| hemB | hemN | SBG_0328 | SBG_3528 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Oxygen-independent coproporphyrinogen III oxidase. | 0.527 |
| hemE | hemB | SBG_3641 | SBG_0328 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.840 |
| hemE | hemF | SBG_3641 | SBG_2247 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.961 |
| hemE | hemG | SBG_3641 | SBG_3518 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | Protoporphyrinogen oxidase. | 0.832 |
| hemE | hemH | SBG_3641 | SBG_0435 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.978 |
| hemE | hemN | SBG_3641 | SBG_3528 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | Oxygen-independent coproporphyrinogen III oxidase. | 0.972 |
| hemF | amiA | SBG_2247 | SBG_2246 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Putative N-acetylmuramoyl-L-alanine amidase. | 0.877 |
| hemF | hemB | SBG_2247 | SBG_0328 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.612 |
| hemF | hemE | SBG_2247 | SBG_3641 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.961 |
| hemF | hemG | SBG_2247 | SBG_3518 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Protoporphyrinogen oxidase. | 0.961 |
| hemF | hemH | SBG_2247 | SBG_0435 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.653 |
| hemF | hemN | SBG_2247 | SBG_3528 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Oxygen-independent coproporphyrinogen III oxidase. | 0.985 |
| hemF | nuoC | SBG_2247 | SBG_2112 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | NADH dehydrogenase I chain C; chain D; Belongs to the complex I 49 kDa subunit family. | 0.534 |
| hemF | ubiF_2 | SBG_2247 | SBG_2649 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Putative monooxygenase. | 0.537 |
| hemF | visB | SBG_2247 | SBG_2650 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.574 |