STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisShistidyl-tRNA synthetase. (424 aa)    
Predicted Functional Partners:
SBOV25871_2
Putative membrane protein.
    0.940
thrS
Conserved hypothetical protein (remnant); Represents the very 5' region of what appears to be a gene remnant.
  
 
 0.913
aspS
aspartyl-tRNA synthetase.
 
  
 0.890
yfgL_1
Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
    0.865
gcpE
GcpE protein (protein E).
  
  
 0.822
ileS
isoleucyl-tRNA synthetase.
 
  
 0.814
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
  
 
 0.764
glyQ
glycine-tRNA synthetase, alpha subunit.
 
  
 0.754
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
 
 0.735
hisI
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase.
  
  
 0.722
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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