STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypEHydrogenase isoenzymes formation protein HypE. (322 aa)    
Predicted Functional Partners:
hypD
Hydrogenase isoenzymes formation protein HypD; Belongs to the HypD family.
 
 
 0.999
hypC
Hydrogenase isoenzymes formation protein HypC.
 
 
 0.995
hypf
Hydrogenase maturation protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 0.987
hypB
Hydrogenase isoenzymes formation protein HypB.
 
  
 0.973
hybG
Putative ABC-transport protein,periplasmic-binding component (pseudogene); Hydrogenase-2 biosynthetic operon.
 
 
 0.953
porB
Putative pyruvate-flavodoxin oxidoreductase.
  
  
 0.920
hypA
HypA protein.
 
  
 0.896
hycE
Formate hydrogenlyase subunit 5.
 
 
 
 0.818
hybF
Hydrogenase-2 component protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.805
SBG_1357
Putative hydrogenase.
 
  
 0.794
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.