| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alaS | yqgF | SBG_2447 | SBG_2697 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.629 |
| gshB | rsmE | SBG_2695 | SBG_2694 | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.778 |
| gshB | yqgE | SBG_2695 | SBG_2696 | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.689 |
| gshB | yqgF | SBG_2695 | SBG_2697 | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.563 |
| miaA | yqgF | SBG_3804 | SBG_2697 | tRNA delta-2-isopentenylpyrophosphate (IPP) transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.588 |
| rsmE | gshB | SBG_2694 | SBG_2695 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.778 |
| rsmE | yqgE | SBG_2694 | SBG_2696 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.519 |
| rsmE | yqgF | SBG_2694 | SBG_2697 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.553 |
| ruvA | yqgF | SBG_1732 | SBG_2697 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.404 |
| yaeQ | yqgF | SBG_0230 | SBG_2697 | Conserved hypothetical protein. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.832 |
| yqgE | gshB | SBG_2696 | SBG_2695 | Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.689 |
| yqgE | rsmE | SBG_2696 | SBG_2694 | Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.519 |
| yqgE | yqgF | SBG_2696 | SBG_2697 | Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.993 |
| yqgF | alaS | SBG_2697 | SBG_2447 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.629 |
| yqgF | gshB | SBG_2697 | SBG_2695 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.563 |
| yqgF | miaA | SBG_2697 | SBG_3804 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | tRNA delta-2-isopentenylpyrophosphate (IPP) transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.588 |
| yqgF | rsmE | SBG_2697 | SBG_2694 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.553 |
| yqgF | ruvA | SBG_2697 | SBG_1732 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.404 |
| yqgF | yaeQ | SBG_2697 | SBG_0230 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Conserved hypothetical protein. | 0.832 |
| yqgF | yqgE | SBG_2697 | SBG_2696 | Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family. | 0.993 |