STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoDRNA polymerase sigma-70 factor. (660 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta-subunit; Belongs to the RNA polymerase beta chain family.
 
 
 0.986
rpoA
DNA-directed RNA polymerase alpha chain.
 
 
 0.980
rpoC
DNA-directed RNA polymerase, beta'-subunit.
 
 
 0.965
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.961
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.957
cap
Cyclic AMP receptor protein,catabolite gene activator.
    
 
 0.947
rsD
Putative regulatory protein; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
   
 
 0.933
gyrB
DNA gyrase subunit B.
 
 
 0.907
dksA
Dosage-dependent dnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
  
 
 
 0.899
sspA
Stringent starvation protein A; Belongs to the GST superfamily.
    
   0.891
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.