STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bisCBiotin sulfoxide reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (777 aa)    
Predicted Functional Partners:
bioB
Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
     
  0.900
birA
Bifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
  0.900
pbpC
Penicillin-binding protein 1C.
   
  
 0.831
torC2
Cytochrome c-type protein; Also significantly similar to SBG3384 49% identity in 366 aa overlap.
 
 
 0.688
torC
Cytochrome c-type protein; Also significantly similar to SBG2025 49% identity in 366 aa overlap.
 
 
 0.634
yedY
Conserved hypothetical protein.
      
 0.621
napC
Cytochrome c-type protein NapC.
 
 
 0.605
porB
Putative pyruvate-flavodoxin oxidoreductase.
  
  
 0.593
napB
Cytochrome c-type protein NapB precursor; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.
 
 
 0.564
gltB
Glutamate synthase [NADPH] large chain precursor.
  
 
 0.561
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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