STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
hslSHeat shock protein B; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent. (142 aa)    
Predicted Functional Partners:
hslT
Heat shock protein A.
 
  
0.859
SBG_1095
Conserved hypothetical protein (pseudogene); Signal peptide predicted for SBG1094 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.992 between residues 40 and 41.
 
  
0.761
clpB
ClpB protein (heat shock protein f84.1); Belongs to the ClpA/ClpB family.
  
 
 0.720
dnaK
DnaK protein (heat shock protein 70).
  
 
 0.679
yidE
Putative membrane protein.
     
 0.674
clpV1_3
Type VI secretion protein (ClpV); Belongs to the ClpA/ClpB family.
  
 
 0.636
clpA
ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.
  
 
 0.622
malT
MalT regulatory protein.
    
 
 0.527
htpG
Heat shock protein HtpG.
  
 
 0.515
hslO_1
Heat shock protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.
  
  
 0.486
Your Current Organism:
Salmonella bongori
NCBI taxonomy Id: 218493
Other names: S. bongori NCTC 12419, Salmonella bongori NCTC 12419, Salmonella bongori str. NCTC 12419, Salmonella bongori strain NCTC 12419
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.