Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
agaSPutative tagatose-6-phosphate aldose/ketose isomerase. (391 aa)    
Predicted Functional Partners:
lacC2
Tagatose-6-phosphate kinase 2; Similar to SUB1455, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-310:1-311); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.942
SUB0038
GntR family regulatory protein; Similar to the C-terminal Streptococcus agalactiae (serotype V) bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase] UniProt:PUR9_STRA5 (EMBL:AE014193) (515 aa) fasta scores: E()=9.7e-16, 85.000% id in 60 aa. Similar to the C-terminal region of SUB0030. Similar to the C-terminal region of SUB0030, 88.333% identity (88.333% ungapped) in 60 aa overlap (1-60:456-515).
 
  
 0.930
lacC1
Tagatose-6-phosphate kinase 1; Similar to SUB0795, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-311:1-310); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.922
SUB0185
Sugar phosphotransferase system (PTS), fructose-specific family, IIA component.
  
 
 0.914
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.906
lacA2
Galactose-6-phosphate isomerase LacA subunit 2; Similar to SUB1457, 74.286% identity (74.286% ungapped) in 140 aa overlap (1-140:1-140).
     
  0.900
lacB2
Galactose-6-phosphate isomerase LacB subunit 2; Similar to SUB1456, 77.778% identity (77.778% ungapped) in 171 aa overlap (1-171:1-171).
     
  0.900
lacB1
Galactose-6-phosphate isomerase LacB subunit 1; Similar to SUB0794, 77.778% identity (77.778% ungapped) in 171 aa overlap (1-171:1-171).
     
  0.900
lacA1
Galactose-6-phosphate isomerase LacA subunit 1; Similar to SUB0793, 74.286% identity (74.286% ungapped) in 140 aa overlap (1-140:1-140).
     
  0.900
lacD3
Tagatose 1,6-diphosphate aldolase 3; Similar to SUB1454, 97.214% identity (97.214% ungapped) in 323 aa overlap (4-326:3-325); and SUB0796, 75.000% identity (75.232% ungapped) in 324 aa overlap (4-326:3-326); Belongs to the aldolase LacD family.
 
     0.862
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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