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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacD3Tagatose 1,6-diphosphate aldolase 3; Similar to SUB1454, 97.214% identity (97.214% ungapped) in 323 aa overlap (4-326:3-325); and SUB0796, 75.000% identity (75.232% ungapped) in 324 aa overlap (4-326:3-326); Belongs to the aldolase LacD family. (326 aa)    
Predicted Functional Partners:
lacC2
Tagatose-6-phosphate kinase 2; Similar to SUB1455, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-310:1-311); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.952
lacC1
Tagatose-6-phosphate kinase 1; Similar to SUB0795, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-311:1-310); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.948
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.905
lacD2
Tagatose 1,6-diphosphate aldolase 2; Similar to SUB1454, 75.460% identity (75.692% ungapped) in 326 aa overlap (1-326:1-325); and SUB0040, 75.000% identity (75.232% ungapped) in 324 aa overlap (3-326:4-326); Belongs to the aldolase LacD family.
  
  
 
0.901
lacD1
Tagatose 1,6-diphosphate aldolase 1; Similar to SUB0040, 97.214% identity (97.214% ungapped) in 323 aa overlap (3-325:4-326); and SUB0796, 75.460% identity (75.692% ungapped) in 326 aa overlap (1-325:1-326); Belongs to the aldolase LacD family.
  
  
 
0.900
agaS
Putative tagatose-6-phosphate aldose/ketose isomerase.
 
   
 0.862
gapN
Putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase.
   
 
  0.819
dgoA
Putative 2-dehydro-3-deoxy-6-phosphogalactonate aldolase.
     
  0.800
kgdA
Putative transposase (fragment); Predicted helix-turn-helix motif with score 996.000, SD 2.58 at aa 24-45, sequence VSWTQLETQFGVNLSNLKYTIR.
     
  0.800
SUB0038
GntR family regulatory protein; Similar to the C-terminal Streptococcus agalactiae (serotype V) bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase] UniProt:PUR9_STRA5 (EMBL:AE014193) (515 aa) fasta scores: E()=9.7e-16, 85.000% id in 60 aa. Similar to the C-terminal region of SUB0030. Similar to the C-terminal region of SUB0030, 88.333% identity (88.333% ungapped) in 60 aa overlap (1-60:456-515).
  
    0.721
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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