Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adhEAldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (882 aa)    
Predicted Functional Partners:
pfl
Formate acetyltransferase.
 
 
 0.962
pta
Putative phosphate acetyltransferase.
   
 
 0.929
atoA2
Acetate CoA-transferase beta subunit 2.
  
 
 0.925
atoD2
Acetate CoA-transferase alpha subunit 2.
  
 
 0.919
atoB2
acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.915
thlA
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.915
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 
 0.908
fabE
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
 0.907
SUB1801
Putative coenzyme A transferase; Belongs to the 3-oxoacid CoA-transferase family.
    
 0.906
accC
Biotin carboxylase subunit of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
 
 0.905
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.