pflD protein (Streptococcus uberis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pflD

Putative formate acetyltransferase. (804 aa)

Predicted Functional Partners:

acoL

0.937

adhE

0.931

pdhB

0.925

SUB0825

0.922

pdhA

0.920

pta

0.919

ldh

0.918

pdhC

0.917

pyk

0.916

pfl

0.916

Your Current Organism:

Streptococcus uberis

NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SUB0825	acoL	SUB0825	SUB1100	NAD-dependent malic enzyme.	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	0.691
SUB0825	ldh	SUB0825	SUB0879	NAD-dependent malic enzyme.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	0.942
SUB0825	pdhA	SUB0825	SUB1103	NAD-dependent malic enzyme.	Putative pyruvate dehydrogenase E1 component, alpha subunit.	0.925
SUB0825	pdhB	SUB0825	SUB1102	NAD-dependent malic enzyme.	Putative pyruvate dehydrogenase E1 component, beta subunit.	0.929
SUB0825	pfl	SUB0825	SUB1568	NAD-dependent malic enzyme.	Formate acetyltransferase.	0.922
SUB0825	pflD	SUB0825	SUB0160	NAD-dependent malic enzyme.	Putative formate acetyltransferase.	0.922
SUB0825	pta	SUB0825	SUB0855	NAD-dependent malic enzyme.	Putative phosphate acetyltransferase.	0.927
SUB0825	pyk	SUB0825	SUB1000	NAD-dependent malic enzyme.	Putative pyruvate kinase; Belongs to the pyruvate kinase family.	0.950
acoL	SUB0825	SUB1100	SUB0825	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	NAD-dependent malic enzyme.	0.691
acoL	adhE	SUB1100	SUB0063	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	Aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.437
acoL	ldh	SUB1100	SUB0879	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	0.767
acoL	pdhA	SUB1100	SUB1103	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	Putative pyruvate dehydrogenase E1 component, alpha subunit.	0.999
acoL	pdhB	SUB1100	SUB1102	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	Putative pyruvate dehydrogenase E1 component, beta subunit.	0.999
acoL	pdhC	SUB1100	SUB1101	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.994
acoL	pfl	SUB1100	SUB1568	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	Formate acetyltransferase.	0.937
acoL	pflD	SUB1100	SUB0160	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	Putative formate acetyltransferase.	0.937
acoL	pta	SUB1100	SUB0855	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	Putative phosphate acetyltransferase.	0.692
acoL	pyk	SUB1100	SUB1000	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	Putative pyruvate kinase; Belongs to the pyruvate kinase family.	0.548
adhE	acoL	SUB0063	SUB1100	Aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.	0.437
adhE	pdhC	SUB0063	SUB1101	Aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.917