Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SUB0178CAAX amino terminal protease family protein. (309 aa)    
Predicted Functional Partners:
SUB1152
Putative glutamine ABC transporter, glutamine-binding protein/permease protein.
  
  
 0.762
SUB1270
Conserved hypothetical protein; Possible alternative translational start site after codon 4.
      
 0.623
SUB0117
Conserved hypothetical protein.
      
 0.612
SUB1104
ABC transporter ATP-binding protein.
     
 0.608
SUB0176
Putative exported protein.
       0.560
SUB0177
RNA polymerase sigma factor protein; Possible alternative translational start site; Belongs to the sigma-70 factor family. ECF subfamily.
       0.554
SUB1663
ABC-2 type transporter membrane protein.
  
  
 0.451
uvrB
UvrABC system protein B (UvrB protein); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits [...]
       0.443
SUB0527
Nitroreductase family protein.
  
  
 0.404
SUB1055
Nitroreductase family protein.
  
  
 0.404
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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