Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SUB0187Sugar phosphotransferase system (PTS), mannose/fructose family, IIC component. (285 aa)    
Predicted Functional Partners:
SUB0186
Sugar phosphotransferase system (PTS), sorbose subfamily, IIB component.
 
 0.998
manZ
Sugar phosphotransferase system (PTS), mannose/fructose/sorbose family, IID component.
 
 0.995
manL
Putative mannose-specific phosphotransferase system (PTS), IIAB component.
 
 0.993
SUB0185
Sugar phosphotransferase system (PTS), fructose-specific family, IIA component.
 
 
 0.982
SUB0045
Sugar phosphotransferase system (PTS), mannose/fructose/sorbose family, IID component.
 0.981
manN
Putative mannose-specific phosphotransferase system (PTS), IIC component (pseudogene); HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 1.4e-132.
 0.981
SUB0189
Putative membrane protein.
 
     0.952
SUB0046
Sugar phosphotransferase system (PTS), fructose family, IIA component.
 
 0.946
SUB0044
Sugar phosphotransferase system (PTS), sorbose-specific family, IIC component.
  
  
  0.920
ptsH
Histidine-containing phosphocarrier protein (HPr).
    
 0.917
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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