Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
SUB0189Putative membrane protein. (105 aa)    
Predicted Functional Partners:
SUB0187
Sugar phosphotransferase system (PTS), mannose/fructose family, IIC component.
 
     0.952
manZ
Sugar phosphotransferase system (PTS), mannose/fructose/sorbose family, IID component.
 
     0.947
SUB0186
Sugar phosphotransferase system (PTS), sorbose subfamily, IIB component.
 
     0.945
SUB0185
Sugar phosphotransferase system (PTS), fructose-specific family, IIA component.
 
     0.938
SUB0184
Extracellular sugar-binding protein.
 
    0.869
SUB0182
Sensor histidine kinase.
 
     0.858
SUB0183
Response regulator protein.
 
     0.827
SUB0181
Putative extracellular sugar-binding protein.
 
     0.754
groEL
Putative surface-anchored protein (pseudogene); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
       0.443
groES
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
       0.443
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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