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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). (707 aa)    
Predicted Functional Partners:
SUB0263
Ppx/GppA phosphatase family protein.
 
 
 0.984
ppaC
Manganese-dependent inorganic pyrophosphatase.
     
  0.900
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.602
SUB0940
Similar to Bacillus pseudofirmus cardiolipin synthetase Cls UniProt:CLS_BACPF (EMBL:U88888) (503 aa) fasta scores: E()=2.1e-52, 31.944% id in 504 aa, and to Streptococcus pyogenes (serotype M6) cardiolipin synthetase Cls UniProt:Q5XC13_STRP6 (EMBL:CP000003) (525 aa) fasta scores: E()=9.2e-164, 78.812% id in 505 aa. CDS is truncated at the N-terminus in comparison to some orthologues. Similarity extends beyond the marked translational start, but the extended CDS lacks an appropriate translational start site. Possible pseudogene; Belongs to the phospholipase D family. Cardiolipin synthas [...]
  
  
 0.532
SUB0264
Crp family regulatory protein.
  
  
 0.499
SUB0261
PAP2 superfamily.
       0.439
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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