Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SUB0274Conserved hypothetical protein. (171 aa)    
Predicted Functional Partners:
SUB0273
Putative membrane protein (fragment); Probable gene remnant. Similar to the N-terminal regions of Streptococcus pyogenes (serotype M18) hypothetical protein spym18_2006. UniProt:Q8NZD2_STRP8 (EMBL:AE010104) (265 aa) fasta scores: E()=3.1e-05, 28.777% id in 139 aa, and Streptococcus pyogenes hypothetical protein spy1939. UniProt:Q99Y01_STRPY (EMBL:AE006617) (265 aa) fasta scores: E()=3.1e-05, 28.777% id in 139 aa. Missing C-terminal region contains transmembrane domain; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
  
 0.976
mrnC
Conserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
 
  
 0.824
SUB1286
Conserved hypothetical protein.
  
  
 0.704
SUB0275
DegV family protein.
       0.678
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.565
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
       0.564
SUB0008
Putative polysaccharide biosynthesis protein.
  
     0.538
SUB0177
RNA polymerase sigma factor protein; Possible alternative translational start site; Belongs to the sigma-70 factor family. ECF subfamily.
 
    0.510
rpsI
30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
       0.493
SUB1472
Phosphotransferase enzyme family protein.
  
     0.488
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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