STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB0286Similar to Bacillus methanolicus 6-phospho-3-hexuloisomerase Phi UniProt:Q6TV53_BACMT (EMBL:AY386313) (184 aa) fasta scores: E()=3.7e-20, 38.764% id in 178 aa. (188 aa)    
Predicted Functional Partners:
tkt2
Putative transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.961
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.929
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.924
RPE
Putative ribulose-phosphate 3-epimerase; Similar to the C-terminal region of Spinacia oleracea (Spinach) ribulose-phosphate 3-epimerase, chloroplast precursor RPE (ec 5.1.3.1) (pentose-5-phosphate 3-epimerase) UniProt:RPE_SPIOL (EMBL:AF070941) (285 aa) fasta scores: E()=2.9e-21, 38.614% id in 202 aa.
 
  
 0.917
fbp
Putative fructose-1,6-bisphosphatase.
     
  0.900
SUB1757
Putative transketolase subunit; Similar to the C-terminal region of Homo sapiens (Human) transketolase TKT UniProt:TKT_HUMAN (EMBL:HSTRANSKE) (623 aa) fasta scores: E()=2.7e-17, 27.213% id in 305 aa.
     
  0.900
SUB1758
Putative transketolase subunit; Similar to the N-terminal region of Homo sapiens (Human) transketolase TKT UniProt:TKT_HUMAN (EMBL:HSTRANSKE) (623 aa) fasta scores: E()=9.4e-24, 34.286% id in 280 aa.
     
  0.900
mtlD-2
Putative mannitol-1-phosphate 5-dehydrogenase.
 
   
 0.888
SUB0289
Putative mannitol-specific phosphotransferase system (PTS), IIBC component; Similar to the N-terminal region of Escherichia coli PTS system, mannitol-specific IIABC component MtlA UniProt:PTMA_ECOLI (EMBL:ECUW76) (637 aa) fasta scores: E()=6.9e-92, 51.502% id in 466 aa; Similar to the N-terminal region of SUB0997, 50.951% identity (51.940% ungapped) in 473 aa overlap (1-466:1-471).
 
   
 0.878
SUB0288
Sugar phosphotransferase system (PTS), IIA component.
  
  
 0.871
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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