Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtlD-2Putative mannitol-1-phosphate 5-dehydrogenase. (392 aa)    
Predicted Functional Partners:
SUB0289
Putative mannitol-specific phosphotransferase system (PTS), IIBC component; Similar to the N-terminal region of Escherichia coli PTS system, mannitol-specific IIABC component MtlA UniProt:PTMA_ECOLI (EMBL:ECUW76) (637 aa) fasta scores: E()=6.9e-92, 51.502% id in 466 aa; Similar to the N-terminal region of SUB0997, 50.951% identity (51.940% ungapped) in 473 aa overlap (1-466:1-471).
 
 
 0.998
mtlF
Putative mannitol-specific phosphotransferase system (PTS), IIA component.
 
 0.993
SUB0288
Sugar phosphotransferase system (PTS), IIA component.
 
 
 0.992
mtlA
Putative mannitol-specific phosphotransferase system (PTS), IIBC component; N-terminal region is similar to SUB0289, 50.951% identity (51.940% ungapped) in 473 aa overlap (1-471:1-466).
 
 
 0.988
mtlD
Mannitol-1-phosphate 5-dehydrogenase.
  
  
 
0.917
sorD
Sorbitol-6-phosphate 2-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.916
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.914
fbp
Putative fructose-1,6-bisphosphatase.
     
 0.912
pmi
Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.908
scrK2
Similar to SUB1542, 69.310% identity (69.310% ungapped) in 290 aa overlap (1-290:4-293).
  
 
 0.904
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.