Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SUB0292Hypothetical protein; No significant database matches. (37 aa)    
Predicted Functional Partners:
tkt2
Putative transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
       0.628
tal2
Probable transaldolase 2; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
       0.495
mtlD-2
Putative mannitol-1-phosphate 5-dehydrogenase.
       0.480
SUB0288
Sugar phosphotransferase system (PTS), IIA component.
       0.480
SUB0289
Putative mannitol-specific phosphotransferase system (PTS), IIBC component; Similar to the N-terminal region of Escherichia coli PTS system, mannitol-specific IIABC component MtlA UniProt:PTMA_ECOLI (EMBL:ECUW76) (637 aa) fasta scores: E()=6.9e-92, 51.502% id in 466 aa; Similar to the N-terminal region of SUB0997, 50.951% identity (51.940% ungapped) in 473 aa overlap (1-466:1-471).
       0.480
RPE
Putative ribulose-phosphate 3-epimerase; Similar to the C-terminal region of Spinacia oleracea (Spinach) ribulose-phosphate 3-epimerase, chloroplast precursor RPE (ec 5.1.3.1) (pentose-5-phosphate 3-epimerase) UniProt:RPE_SPIOL (EMBL:AF070941) (285 aa) fasta scores: E()=2.9e-21, 38.614% id in 202 aa.
       0.471
SUB0286
Similar to Bacillus methanolicus 6-phospho-3-hexuloisomerase Phi UniProt:Q6TV53_BACMT (EMBL:AY386313) (184 aa) fasta scores: E()=3.7e-20, 38.764% id in 178 aa.
       0.471
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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