Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sufDConserved hypothetical protein; In S. thermophilus sufD mutant displayed increased sensitivity to superoxide radicals compared to the wild type. SufD is likely to play a major role in oxidative stress defense, possibly resulting from its role in [Fe-S] cluster assembly and/or repair. (423 aa)    
Predicted Functional Partners:
sufC
Putative ABC transporter, ATP-binding protein.
 
 
 0.998
csdB
Putative cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
 
 0.998
iscU
NifU-like protein; In S. thermophilus iscU mutant displayed increased sensitivity to superoxide radicals compared to the wild type. IscU is likely to play a major role in oxidative stress defense, possibly resulting from its role in [Fe-S] cluster assembly and/or repair.
 
  
 0.995
sufB
Conserved hypothetical protein.
 
  
0.965
SUB0693
Conserved hypothetical protein.
 
   
 0.762
mecA
Adapter protein MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
       0.538
rgpG
Putative glycosyl transferase.
       0.538
bacA
Undecaprenol kinase (bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.519
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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