comX protein (Streptococcus uberis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

comX

Putative competence-specific global transcription modulator. (162 aa)

Predicted Functional Partners:

ftsH

0.529

hpt

0.527

eep

0.521

pnpA

0.510

SUB0353

0.491

SUB0354

0.491

Your Current Organism:

Streptococcus uberis

NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SUB0353	SUB0354	SUB0353	SUB0354	Conserved hypothetical protein.	GTP-binding protein.	0.887
SUB0353	comX	SUB0353	SUB0352	Conserved hypothetical protein.	Putative competence-specific global transcription modulator.	0.491
SUB0354	SUB0353	SUB0354	SUB0353	GTP-binding protein.	Conserved hypothetical protein.	0.887
SUB0354	comX	SUB0354	SUB0352	GTP-binding protein.	Putative competence-specific global transcription modulator.	0.491
comX	SUB0353	SUB0352	SUB0353	Putative competence-specific global transcription modulator.	Conserved hypothetical protein.	0.491
comX	SUB0354	SUB0352	SUB0354	Putative competence-specific global transcription modulator.	GTP-binding protein.	0.491
comX	eep	SUB0352	SUB0254	Putative competence-specific global transcription modulator.	Putative pheromone-processing membrane metalloprotease.	0.521
comX	ftsH	SUB0352	SUB0015	Putative competence-specific global transcription modulator.	Putative cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.529
comX	hpt	SUB0352	SUB0014	Putative competence-specific global transcription modulator.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.527
comX	pnpA	SUB0352	SUB0267	Putative competence-specific global transcription modulator.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.510
eep	comX	SUB0254	SUB0352	Putative pheromone-processing membrane metalloprotease.	Putative competence-specific global transcription modulator.	0.521
eep	ftsH	SUB0254	SUB0015	Putative pheromone-processing membrane metalloprotease.	Putative cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.417
eep	pnpA	SUB0254	SUB0267	Putative pheromone-processing membrane metalloprotease.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.634
ftsH	comX	SUB0015	SUB0352	Putative cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Putative competence-specific global transcription modulator.	0.529
ftsH	eep	SUB0015	SUB0254	Putative cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Putative pheromone-processing membrane metalloprotease.	0.417
ftsH	hpt	SUB0015	SUB0014	Putative cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.957
ftsH	pnpA	SUB0015	SUB0267	Putative cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.571
hpt	comX	SUB0014	SUB0352	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	Putative competence-specific global transcription modulator.	0.527
hpt	ftsH	SUB0014	SUB0015	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	Putative cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.957
hpt	pnpA	SUB0014	SUB0267	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.511