SUB0359 protein (Streptococcus uberis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SUB0359

Conserved hypothetical protein. (246 aa)

Predicted Functional Partners:

rsfS

0.951

SUB0357

0.863

SUB0355

0.826

tmcAL

0.803

nadD

0.794

SUB0354

0.704

SUB0353

0.662

SUB1858

0.452

SUB0364

0.443

fps

0.427

Your Current Organism:

Streptococcus uberis

NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SUB0353	SUB0354	SUB0353	SUB0354	Conserved hypothetical protein.	GTP-binding protein.	0.911
SUB0353	SUB0355	SUB0353	SUB0355	Conserved hypothetical protein.	Conserved hypothetical protein.	0.800
SUB0353	SUB0357	SUB0353	SUB0357	Conserved hypothetical protein.	Conserved hypothetical protein.	0.849
SUB0353	SUB0359	SUB0353	SUB0359	Conserved hypothetical protein.	Conserved hypothetical protein.	0.662
SUB0353	nadD	SUB0353	SUB0356	Conserved hypothetical protein.	Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.779
SUB0353	rsfS	SUB0353	SUB0358	Conserved hypothetical protein.	Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.717
SUB0353	tmcAL	SUB0353	SUB0360	Conserved hypothetical protein.	Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.	0.613
SUB0354	SUB0353	SUB0354	SUB0353	GTP-binding protein.	Conserved hypothetical protein.	0.911
SUB0354	SUB0355	SUB0354	SUB0355	GTP-binding protein.	Conserved hypothetical protein.	0.895
SUB0354	SUB0357	SUB0354	SUB0357	GTP-binding protein.	Conserved hypothetical protein.	0.829
SUB0354	SUB0359	SUB0354	SUB0359	GTP-binding protein.	Conserved hypothetical protein.	0.704
SUB0354	nadD	SUB0354	SUB0356	GTP-binding protein.	Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.851
SUB0354	rsfS	SUB0354	SUB0358	GTP-binding protein.	Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.904
SUB0354	tmcAL	SUB0354	SUB0360	GTP-binding protein.	Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.	0.613
SUB0355	SUB0353	SUB0355	SUB0353	Conserved hypothetical protein.	Conserved hypothetical protein.	0.800
SUB0355	SUB0354	SUB0355	SUB0354	Conserved hypothetical protein.	GTP-binding protein.	0.895
SUB0355	SUB0357	SUB0355	SUB0357	Conserved hypothetical protein.	Conserved hypothetical protein.	0.869
SUB0355	SUB0359	SUB0355	SUB0359	Conserved hypothetical protein.	Conserved hypothetical protein.	0.826
SUB0355	nadD	SUB0355	SUB0356	Conserved hypothetical protein.	Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.902
SUB0355	rsfS	SUB0355	SUB0358	Conserved hypothetical protein.	Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.874