SUB0385 protein (Streptococcus uberis) - STRING interaction network

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Score

SUB0385

Putative helicase. (1029 aa)

Predicted Functional Partners:

rpoZ

0.960

rpoB

0.958

rpoA

0.953

polA

0.935

rpoC

0.803

dnaN

0.771

udk

0.769

dinG

0.758

recA

0.742

topA

0.705

Your Current Organism:

Streptococcus uberis

NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SUB0385	dinG	SUB0385	SUB0627	Putative helicase.	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	0.758
SUB0385	dnaN	SUB0385	SUB0002	Putative helicase.	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	0.771
SUB0385	polA	SUB0385	SUB1716	Putative helicase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.935
SUB0385	recA	SUB0385	SUB1778	Putative helicase.	RecA recombinase (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.742
SUB0385	rpoA	SUB0385	SUB0094	Putative helicase.	DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.953
SUB0385	rpoB	SUB0385	SUB0115	Putative helicase.	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.958
SUB0385	rpoC	SUB0385	SUB0116	Putative helicase.	DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.803
SUB0385	rpoZ	SUB0385	SUB1390	Putative helicase.	DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.960
SUB0385	topA	SUB0385	SUB0925	Putative helicase.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.705
SUB0385	udk	SUB0385	SUB1217	Putative helicase.	Uridine kinase.	0.769
dinG	SUB0385	SUB0627	SUB0385	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	Putative helicase.	0.758
dinG	dnaN	SUB0627	SUB0002	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	0.794
dinG	polA	SUB0627	SUB1716	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.908
dinG	recA	SUB0627	SUB1778	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	RecA recombinase (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.644
dinG	rpoA	SUB0627	SUB0094	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.927
dinG	rpoB	SUB0627	SUB0115	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.923
dinG	rpoC	SUB0627	SUB0116	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.744
dinG	rpoZ	SUB0627	SUB1390	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.920
dinG	topA	SUB0627	SUB0925	Putative ATP-dependent DNA helicase; 3'-5' exonuclease.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.755
dnaN	SUB0385	SUB0002	SUB0385	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Putative helicase.	0.771