STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPutative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (364 aa)    
Predicted Functional Partners:
SUB0447
Putative D-isomer specific 2-hydroxyacid dehydrogenase.
 
 0.997
SUB0651
Haloacid dehalogenase-like hydrolase; Similar to Shigella flexneri phosphoserine phosphatase SerB UniProt:SERB_ECOLI (EMBL:AE016993) (322 aa) fasta scores: E()=2.9e-24, 46.117% id in 206 aa, and to the full length Streptococcus thermophilus (strain ATCC BAA-250/LMG 18311) phosphoserine phosphatase SerB UniProt:Q5M3B3_STRTR (215 aa) fasta scores: E()=2.2e-46, 68.224% id in 214 aa.
  
 
 0.949
SUB0065
Putative threonine synthase.
   
 0.938
cysM
Putative cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.927
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
    
 0.784
SUB0446
Acetyltransferase (GNAT) family protein.
     
 0.765
hom
Homoserine dehydrogenase.
  
  
 0.671
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.642
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
  
  
 0.639
acoL
HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.
  
  
 0.628
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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