Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtuAPreviously sequenced as Streptococcus uberis extracellular manganese-binding protein MtuA UniProt:Q70UQ6 (EMBL:SUB539135) (310 aa) fasta scores: E()=1.1e-111, 100.000% id in 310 aa; Belongs to the bacterial solute-binding protein 9 family. (310 aa)    
Predicted Functional Partners:
mtsB
Metal cation ABC transporter ATP-binding protein.
 
 
 0.999
mtsC
Metal cation ABC transporter membrane protein.
 
 0.999
SUB0112
ABC transporter permease protein.
 
  
 0.910
scaR
Metal-dependent transcriptional regulator.
  
  
 0.899
SUB0111
ABC transporter ATP-binding protein.
 
  
 0.853
fbpS
Fibronectin/fibrinogen-binding protein.
      
 0.748
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
      
 0.638
tpx
Putative thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
     
 0.600
adcA
Zinc-binding protein AdcA precursor; Belongs to the bacterial solute-binding protein 9 family.
 
  
0.581
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.545
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (20%) [HD]