Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (169 aa)    
Predicted Functional Partners:
msrB
Peptide methionine sulfoxide reductase.
 
 0.990
SUB0487
Conserved hypothetical protein; Belongs to the UPF0346 family.
       0.835
SUB0485
Conserved hypothetical protein; Belongs to the CvfB family.
       0.721
SUB0488
PhoH-like protein.
       0.670
rrf
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
       0.626
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.601
nrdH
Glutaredoxin-like protein.
  
 
 0.546
galE
UDP-glucose 4-epimerase (pseudogene); HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 9e-139.
   
 0.453
SUB0300
Conserved hypothetical protein.
   
 0.453
maa
Maltose O-acetyltransferase.
      0.411
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (14%) [HD]