Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SUB0498Response regulator protein. (246 aa)    
Predicted Functional Partners:
SUB0499
Sensor histidine kinase.
 
 
 0.994
SUB1671
Putative sensor kinase.
 
 
 0.982
SUB1674
Putative sensor kinase (pseudogene); Similar to Streptococcus agalactiae histidine kinase RgfC UniProt:Q8L360_STRAG (EMBL:AF390107) (444 aa) fasta scores: E()=4.5e-24, 26.742% id in 445 aa. CDS contains a frameshift after codon 157.
 
 
 0.982
SUB1675
Putative sensor kinase.
 
 
 0.982
SUB1676
Sensor histidine kinase.
 
 
 0.982
fasA
Response regulator protein.
  
  
 
0.910
SUB0500
Putative membrane protein.
       0.701
SUB0918
Putative transporter permease protein.
 
     0.463
SUB1799
Putative DNA-binding membrane protein (pseudogene); Predicted helix-turn-helix motif with score 2592.000, SD 8.02 at aa 16-37, sequence LSQEDLAEKIYVSRQTISNWEN.
  
     0.415
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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