| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SUB0251 | SUB1732 | SUB0251 | SUB1732 | Putative preprotein translocase subunit. | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | 0.946 |
| SUB0251 | ffh | SUB0251 | SUB0895 | Putative preprotein translocase subunit. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.924 |
| SUB0251 | ftsY | SUB0251 | SUB0559 | Putative preprotein translocase subunit. | Putative cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.925 |
| SUB0251 | rplM | SUB0251 | SUB0276 | Putative preprotein translocase subunit. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.437 |
| SUB0251 | rplU | SUB0251 | SUB0725 | Putative preprotein translocase subunit. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.427 |
| SUB0251 | secA | SUB0251 | SUB1537 | Putative preprotein translocase subunit. | Putative preprotein SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.922 |
| SUB0251 | secG | SUB0251 | SUB0522 | Putative preprotein translocase subunit. | Putative protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.958 |
| SUB0251 | secY | SUB0251 | SUB0088 | Putative preprotein translocase subunit. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.940 |
| SUB0251 | yidC | SUB0251 | SUB0393 | Putative preprotein translocase subunit. | Membrane protein OxaA 2 precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.936 |
| SUB0251 | yidC-2 | SUB0251 | SUB1666 | Putative preprotein translocase subunit. | Membrane protein OxaA 1 precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.936 |
| SUB1732 | SUB0251 | SUB1732 | SUB0251 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | Putative preprotein translocase subunit. | 0.946 |
| SUB1732 | ffh | SUB1732 | SUB0895 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.964 |
| SUB1732 | ftsY | SUB1732 | SUB0559 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | Putative cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.959 |
| SUB1732 | rplM | SUB1732 | SUB0276 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.848 |
| SUB1732 | rplU | SUB1732 | SUB0725 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.774 |
| SUB1732 | secA | SUB1732 | SUB1537 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | Putative preprotein SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.983 |
| SUB1732 | secG | SUB1732 | SUB0522 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | Putative protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.997 |
| SUB1732 | secY | SUB1732 | SUB0088 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.996 |
| SUB1732 | yidC | SUB1732 | SUB0393 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | Membrane protein OxaA 2 precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.956 |
| SUB1732 | yidC-2 | SUB1732 | SUB1666 | Putative preprotein translocase SecE subunit; Belongs to the SecE/SEC61-gamma family. | Membrane protein OxaA 1 precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.956 |