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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vicRResponse regulator protein; Similar to SUB0567, 50.847% identity (52.402% ungapped) in 236 aa overlap (1-233:1-232). (236 aa)    
Predicted Functional Partners:
vicK
Sensor histidine kinase.
 0.998
SUB0202
Sensor histidine kinase.
 
 0.925
phoR
Similar to the C-terminal region of Bacillus subtilis alkaline phosphatase synthesis sensor protein PhoR UniProt:PHOR_BACSU (EMBL:AF008220) (579 aa) fasta scores: E()=2.8e-31, 36.164% id in 365 aa, and to the full length Streptococcus pneumoniae histidine kinase PnpS UniProt:Q9X4S9_STRPN (EMBL:AF118229) (422 aa) fasta scores: E()=2.3e-77, 57.494% id in 407 aa.
 
 0.924
ciaH
Sensor histidine kinase.
 
 0.892
vicX
Metallo-beta-lactamase superfamily protein.
  
  
 0.890
SUB0191
Sensor histidine kinase.
 
 0.883
csrS
Sensor histidine kinase.
 
 0.839
SUB0916
Sensor histidine kinase.
 
 0.730
smc
Putative chromosome partition protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
   
 
 0.575
glnQ4
Putative glutamine transporter, ATP-binding protein 4; Similar to SUB1278, 53.719% identity (54.167% ungapped) in 242 aa overlap (3-244:5-244); and SUB1153, 51.653% identity (52.083% ungapped) in 242 aa overlap (4-245:6-245).
  
  
 0.563
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.