Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
vicRResponse regulator protein; Similar to SUB0567, 50.847% identity (52.402% ungapped) in 236 aa overlap (1-233:1-232). (236 aa)    
Predicted Functional Partners:
vicK
Sensor histidine kinase.
 0.998
phoR
Similar to the C-terminal region of Bacillus subtilis alkaline phosphatase synthesis sensor protein PhoR UniProt:PHOR_BACSU (EMBL:AF008220) (579 aa) fasta scores: E()=2.8e-31, 36.164% id in 365 aa, and to the full length Streptococcus pneumoniae histidine kinase PnpS UniProt:Q9X4S9_STRPN (EMBL:AF118229) (422 aa) fasta scores: E()=2.3e-77, 57.494% id in 407 aa.
 
 0.943
vicX
Metallo-beta-lactamase superfamily protein.
  
  
 0.941
SUB0202
Sensor histidine kinase.
 
 0.922
SUB0191
Sensor histidine kinase.
 
 
 0.877
ciaH
Sensor histidine kinase.
 
 
 0.872
csrS
Sensor histidine kinase.
 
 
 0.825
SUB0916
Sensor histidine kinase.
 
 
 0.736
glnQ4
Putative glutamine transporter, ATP-binding protein 4; Similar to SUB1278, 53.719% identity (54.167% ungapped) in 242 aa overlap (3-244:5-244); and SUB1153, 51.653% identity (52.083% ungapped) in 242 aa overlap (4-245:6-245).
  
  
 0.707
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.693
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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